26 postdoctoral fellow jobs found

Responsibilities The SEPS lab ( http://faculty.washington.edu/seps  ) at the Center for Integrative Brain Research, Seattle Children's Research Institute and the University of Washington invites applications for several R01-funded postdoctoral positions. Work in the SEPS lab focuses on shared molecular pathology among the many genetic causes of autism. The successful candidate will work closely with a technician and graduate/undergraduate students to plan and supervise several parallel lines of investigation involving altered signal transduction in autism, using genetic mouse models and primary neuronal cell cultures. The candidate will be expected to independently move projects forward, write papers, and apply for F32 or equivalent grants.  The ideal candidate will have the ability to perform precise wetlab work and complex bioinformatics analyses using MatLab and R programming. Prior experience in molecular or behavioral biology, and/or working with mouse...

Responsibilities The SEPS lab ( http://faculty.washington.edu/seps  ) at the Center for Integrative Brain Research, Seattle Children's Research Institute and the University of Washington invites applications for several R01-funded postdoctoral positions. Work in the SEPS lab focuses on shared molecular pathology among the many genetic causes of autism. The successful candidate will work closely with a technician and graduate/undergraduate students to plan and supervise several parallel lines of investigation involving altered signal transduction in autism, using genetic mouse models and primary neuronal cell cultures. The candidate will be expected to independently move projects forward, write papers, and apply for F32 or equivalent grants.  The ideal candidate will have the ability to perform precise wetlab work and complex bioinformatics analyses using MatLab and R programming. Prior experience in molecular or behavioral biology, and/or working with mouse...

Responsibilities Postdoctoral Research Associate – Statistical Machine Learning, Computational Biology, and Genomics     Job Summary:   The Genomic Data Modeling lab at Seattle Children’s Research Institute, led by Dr. Mohammadi, seeks highly motivated Postdoc interested in method development to join ongoing systems genetics and precision medicine projects. We use a statistical machine learning approach to address problems in biomedical research, including modeling variation in the non-coding genome, identifying genetic variation that contributes to disease, and analyzing multi-omics data.   Our research is at the interface of Machine Learning and Statistical Genetics. We develop and apply mathematical frameworks, statistical models, and deep learning to address the computational challenges of analyzing genome variation and its effect on human health. We participate in basic research as part of large functional genomics consortia and...

Responsibilities Postdoctoral Research Associate – Statistical Machine Learning, Computational Biology, and Genomics     Job Summary:   The Genomic Data Modeling lab at Seattle Children’s Research Institute, led by Dr. Mohammadi, seeks highly motivated Postdoc interested in method development to join ongoing systems genetics and precision medicine projects. We use a statistical machine learning approach to address problems in biomedical research, including modeling variation in the non-coding genome, identifying genetic variation that contributes to disease, and analyzing multi-omics data.   Our research is at the interface of Machine Learning and Statistical Genetics. We develop and apply mathematical frameworks, statistical models, and deep learning to address the computational challenges of analyzing genome variation and its effect on human health. We participate in basic research as part of large functional genomics consortia and...

Responsibilities Seattle Children’s Innovative Technologies Lab at Seattle Children’s Research Institute, led by Dr. Frederick Shic, seeks postdocs/senior scientists interested in advancing next-generation technologies (mobile applications, emphasizing remote eye tracking) that assess and predict infant development. The primary emphases of this work are on (1) hyper-efficient characterization of developmental/cognitive abilities in infants; and (2) robust prediction of developmental outcomes, especially as related to autism spectrum conditions. Additional areas of focus include: multi-scale evolutionary and adaptive testing methods; biomarker discovery and refinement; developmental modeling; and design and evaluation of methods that are universally applicable, accessible, and robust across sociodemographic strata.   This work combines insights from computer vision, machine learning, AI image generation, and clinical developmental science. Building atop extant...

Responsibilities Seattle Children’s Innovative Technologies Lab at Seattle Children’s Research Institute, led by Dr. Frederick Shic, seeks postdocs/senior scientists interested in advancing next-generation technologies (mobile applications, emphasizing remote eye tracking) that assess and predict infant development. The primary emphases of this work are on (1) hyper-efficient characterization of developmental/cognitive abilities in infants; and (2) robust prediction of developmental outcomes, especially as related to autism spectrum conditions. Additional areas of focus include: multi-scale evolutionary and adaptive testing methods; biomarker discovery and refinement; developmental modeling; and design and evaluation of methods that are universally applicable, accessible, and robust across sociodemographic strata.   This work combines insights from computer vision, machine learning, AI image generation, and clinical developmental science. Building atop extant...

Responsibilities Postdoctoral Fellow – Single-cell Spatial transcriptomics for Lupus research (Computational position)     Job Summary:   The Genomic Data Modeling lab at Seattle Children’s Research Institute, led by Dr. Mohammadi, seeks highly motivated Postdoc interested in method development to join our lab in the context of a recently funded project that aims to understand the biology of human lupus nephritis using single-cell resolution spatial transcriptomics. The postdoctoral associate will work closely with our clinical collaborator lab led by Dr. Shaun Jackson . We use a statistical machine learning approach to address problems in biomedical research, including modeling variation in the non-coding genome, identifying genetic variation that contributes to disease, and analyzing multi-omics data. Our research is at the interface of Machine Learning and Statistical Genetics. We develop and apply mathematical frameworks, statistical...

Responsibilities Postdoctoral Fellow – Single-cell Spatial transcriptomics for Lupus research (Computational position)     Job Summary:   The Genomic Data Modeling lab at Seattle Children’s Research Institute, led by Dr. Mohammadi, seeks highly motivated Postdoc interested in method development to join our lab in the context of a recently funded project that aims to understand the biology of human lupus nephritis using single-cell resolution spatial transcriptomics. The postdoctoral associate will work closely with our clinical collaborator lab led by Dr. Shaun Jackson . We use a statistical machine learning approach to address problems in biomedical research, including modeling variation in the non-coding genome, identifying genetic variation that contributes to disease, and analyzing multi-omics data. Our research is at the interface of Machine Learning and Statistical Genetics. We develop and apply mathematical frameworks, statistical...

Responsibilities The post-doctoral fellow will develop scientific skills as appropriate for this level of training position, and carry out research/development activities in support of assigned research projects. Responsibilities include protocol development and review, data collection and analysis, manuscript and fellowship application preparation, and training in the conduct of clinical trials and research. Requirements Required Education/Experience: -Doctorate degree (PhD/DVM/MD) in specialty area from an accredited university training program - Experience using basic research techniques of specialty area Required Credentials: N/A Preferred: - Previous experience conducting research in the pediatric arena - Experience in protocol and manuscript development and in grant writing   Min to Max Hourly Salary $25.34 - $34.47 /hr Min to Max Annual Salary $65,478.00 -...

Responsibilities The post-doctoral fellow will develop scientific skills as appropriate for this level of training position, and carry out research/development activities in support of assigned research projects. Responsibilities include protocol development and review, data collection and analysis, manuscript and fellowship application preparation, and training in the conduct of clinical trials and research. Requirements Required Education/Experience: -Doctorate degree (PhD/DVM/MD) in specialty area from an accredited university training program - Experience using basic research techniques of specialty area Required Credentials: N/A Preferred: - Previous experience conducting research in the pediatric arena - Experience in protocol and manuscript development and in grant writing   Min to Max Hourly Salary $25.34 - $34.47 /hr Min to Max Annual Salary $65,478.00 -...

Responsibilities The Jaspan laboratory at Seattle Children’s Research Institute has an immediate opening for a postdoctoral fellow.  Our laboratory is broadly interested in the interplay between host microbial and immunological factors as they impact susceptibility to infectious diseases the gut and genital tract. For more: https://www.seattlechildrens.org/research/centers-programs/global-infectious-disease-research/research-areas-and-labs/jaspan-lab/   We are looking for a curious and motivated individual to be a part of our team working on the human virome. The successful candidate will be responsible for integrating large datasets including viral, bacterial and immunologic data, to answer important questions regarding the influence of viral populations at mucosal surfaces to human health. The position may also involve in vitro cell culture and molecular assays to validate findings. An individual with a PhD or MD and strong computational...

Responsibilities The Jaspan laboratory at Seattle Children’s Research Institute has an immediate opening for a postdoctoral fellow.  Our laboratory is broadly interested in the interplay between host microbial and immunological factors as they impact susceptibility to infectious diseases the gut and genital tract. For more: https://www.seattlechildrens.org/research/centers-programs/global-infectious-disease-research/research-areas-and-labs/jaspan-lab/   We are looking for a curious and motivated individual to be a part of our team working on the human virome. The successful candidate will be responsible for integrating large datasets including viral, bacterial and immunologic data, to answer important questions regarding the influence of viral populations at mucosal surfaces to human health. The position may also involve in vitro cell culture and molecular assays to validate findings. An individual with a PhD or MD and strong computational...

Responsibilities There is strong evidence that underrepresentation is an important problem that the health research enterprise must address (see  Women, Minorities and Persons With Disabilities in Science and Engineering ). Fostering diversity by addressing underrepresentation in the research workforce is consistent with Seattle Children’s  vision and values .   A fully supported Postdoctoral Scholar position is available in the *Seattle Tuberculosis Research Advancement Centers (SEATRAC) to characterize immune response of novel vaccines and immune pathology associated with tuberculosis and co-morbidities. Previous experience in cellular immunology, including multiparametric flow cytometry, is required. This Postdoctoral position provides the time, funding, mentorship, experiences and training necessary to foster the early career development of the next generation of researchers.   The postdoctoral fellow will receive funding, focused...

Responsibilities There is strong evidence that underrepresentation is an important problem that the health research enterprise must address (see  Women, Minorities and Persons With Disabilities in Science and Engineering ). Fostering diversity by addressing underrepresentation in the research workforce is consistent with Seattle Children’s  vision and values .   A fully supported Postdoctoral Scholar position is available in the *Seattle Tuberculosis Research Advancement Centers (SEATRAC) to characterize immune response of novel vaccines and immune pathology associated with tuberculosis and co-morbidities. Previous experience in cellular immunology, including multiparametric flow cytometry, is required. This Postdoctoral position provides the time, funding, mentorship, experiences and training necessary to foster the early career development of the next generation of researchers.   The postdoctoral fellow will receive funding, focused...

Responsibilities POSTDOCTORAL FELLOWSHIP POSITION:   The Jackson laboratory ( Jackson Lab (seattlechildrens.org) at Seattle Children’s Research Institute (SCRI) is seeking a motivated postdoctoral fellow to work on projects focused on the pathogenesis and treatment of systemic autoimmunity. The postdoctoral scientist would join a rapidly expanding research program in B cell biology within the Center for Immunity and Immunotherapies at SCRI.( Center for Immunity and Immunotherapies (seattlechildrens.org) . Within this broad research focus, specific projects could include: 1) Delineating the B cell-specific drivers of humoral autoimmunity, in particular systemic lupus erythematosus (SLE). 2) Interrogating the pathogenesis of human lupus nephritis using cutting-edge single cell and spatial transcriptomics. 3) Novel therapeutic strategies for B cell depletion in systemic autoimmunity, including design of bispecific antibodies and drug-regulatable chimeric...

Responsibilities The Gern laboratory in the Center for Global Infectious Disease Research (CGIDR) at Seattle Children’s is seeking an outstanding Postdoctoral Scientist to conduct research investigating spatially-resolved immune responses against tuberculosis. This work will be performed within a highly collaborative team of investigators seeking to understand the barriers to immune protection against TB and to devise strategies to overcome these barriers. The lab utilizes cutting-edge imaging and immunologic approaches to investigate responses to TB in the mouse model and human tissues. The driving purpose behind these efforts is to inform new strategies to combat human TB through host-directed therapies or improved vaccines.   This position requires a Ph.D. in the biomedical sciences. Previous experience in immunology or expertise in a complementary field with a strong interest in learning immunology is required. Previous experience in imaging or bioinformatics...

Responsibilities The Emerson lab focuses on modeling malignant brain tumors (e.g. glioblastoma, high-grade meningioma, etc.) and their interaction with the tumor microenvironment through the use of cerebral organoids and single cell techniques. Experiments will include the use of patient-derived tumor tissue, with the goal of translating findings in the lab to treatments for patients. Highly motivated candidates with strong expertise in scRNAseq and bioinformatic analysis are preferred, even if prior experience is not in the field of brain tumors per se. Experience with embryonic stem cell or induced pluripotent stem cell culture is also a plus.  Besides the exciting projects in translational brain tumor research we offer a great lab environment in the vibrant South Lake Union region of Seattle. The laboratory will support initiatives to promote the scientific careers of postdoctoral trainess. The post-doctoral fellow will develop scientific skills as...

Responsibilities The Aldinger Laboratory ( Aldinger Lab - Center for Integrative Brain Research (seattlechildrens.org)) in the Center for Integrative Brain Research at Seattle Children’s Research Institute seeks a postdoc to lead projects studying neurovascular regulation in the context of neurodevelopment. They will be responsible for conducting independent and creative research related to the overall mission of the laboratory. The projects will use primary and stem cell models of neurodevelopmental disorders, molecular genomics, and high-content imaging. Requirements Required Education/Experience: -Doctorate degree (PhD/DVM/MD) in specialty area from an accredited university training program - Experience using basic research techniques of specialty area Required Credentials: N/A Preferred: - - Previous experience conducting research with primary (neurons, fibroblasts) and stem cell models (iPSCs). - Experience in...

Responsibilities Would you like to help kids born with severe heart defects have better lives while also doing exciting science?   The Nigam lab ( Nigam Lab (seattlechildrens.org) at the Center for Developmental Biology and Regenerative Medicine, Seattle Children’s Research Institute and the Department of immunology, University of Washington invites applications for a postdoctoral position.  Work in the Nigam lab uses basic science and translational approaches to improve the care of children born with severe cardiac defects. The primary focus of the lab seeks to elucidate and find novel treatments for the systemic inflammation that occurs after exposure to cardiopulmonary bypass, which is required for the majority of cardiac surgeries. This project, which has been recently awarded a R01, examines how biomechanical stimuli activate inflammatory responses. As a result, successful candidate will be co-mentored by Dr. Ram Savan in the University of Washington...

Responsibilities Post-Doctoral Fellow / Research Scientist Positions in T cell Immunity to Pathogens and Cancers   Laboratories of Dr. Surojit Sarkar ( Sarkar Lab (seattlechildrens.org) and Dr. Vandana Kalia ( Kalia Lab (seattlechildrens.org) are seeking highly motivated, energetic and inquisitive Scientists interested in translational discoveries into T cell memory and exhaustion in infections, immunizations and solid tumors. Projects in the Lab are investigating gene regulatory networks in exhausted T cells and applying resulting immunomics towards development of novel adoptive immunotherapies to solid tumors. These studies feed directly forward into our seamless pipeline of engineering more efficacious CAR T cells that are long-lived, exhaustion-proof and responsive to checkpoint blockade immunotherapies, thereby aimed at achieving life-long remission from cancer. A parallel newly funded NIH-project on the durability and breadth of immunological...